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pH1N1 Vax Ingredients

 
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Mixin



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PostPosted: Fri Dec 04, 2009 2:30 pm    Post subject: pH1N1 Vax Ingredients Reply with quote

What Glaxo's Pandemrix contains:
Active substance:
Split influenza virus, inactivated, containing antigen* equivalent to: A/California/7/2009 (H1N1)v-like strain (X-179A) 3.75 micrograms** per 0.5 ml dose
*propagated in eggs
** expressed in microgram haemagglutinin
Adjuvant:
The vaccine contains an adjuvant - AS03 to stimulate a better response. This adjuvant contains squalene (10.69 milligrams), DL-a-tocopherol (11.86 milligrams) and polysorbate 80 (4.86 milligrams).
Other ingredients:
The other ingredients are: polysorbate 80, octoxynol 10, thiomersal, sodium chloride, disodium hydrogen phosphate, potassium dihydrogen phosphate, potassium chloride, magnesium chloride, water for injections

What Novartis's Focetria contains:
Active Substance:
Influenza virus surface antigens (haemagglutinin and neuraminidase)* of strain: A/California/7/2009 (H1N1)v like strain (X-181) 7.5 micrograms** per 0.5 ml dose
* propagated in eggs
** expressed in microgram haemagglutinin.
Adjuvant:
The vaccine contains an adjuvant - (MF59C.1) to stimulate a better response. MF59C.1 is an oil/water emulsion containing 9.75 mg squalene, 1.175 mg polysorbate 80 and 1.175 mg sorbitan trioleate in a citrate buffer. Quantities are expressed per 0.5 ml vaccine dose.
Other Ingredients:
The other ingredients are: thiomersal (multidose vial only), sodium chloride, potassium chloride, potassium dihydrogen phosphate, disodium phosphate dihydrate, magnesium chloride hexahydrate, calcium chloride dihydrate, sodium citrate, citric acid and water for injections.

What Baxter AG's Celvapan contains:
Active substance:
Whole virion influenza vaccine, inactivated, containing antigen of pandemic strain*: A/California/07/2009 (H1N1) 7.5 micrograms** per 0.5 ml dose
* propagated in Vero cells (continuous cell line of mammalian origin)
** haemagglutinin
Other ingredients:
The other ingredients are:
trometamol, sodium chloride, water for injections, polysorbate 80.

See each label here: http://www.emea.europa.eu/
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